Cloricromen (Cloricromene) hydrochloride is an orally active platelet inhibitor. Cloricromen hydrochloride inhibits thromboxane B 2 release, β-thromboglobulin , and thrombus formation. Cloricromen hydrochloride inhibits LPS ( HY-D1056 )-induced NF-κB activation, oxidative activity, and TNF-α expression. Cloricromen hydrochloride exhibits protective activity in animal models of shock and peripheral ischaemia. Cloricromen hydrochloride can be used for the research of myocardial ischaemia/reperfusion injury, and ischaemic cerebrovascular disease.
Products | Products > Disease Areas > Nervous System Injury | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Ischemia-Reperfusion Injury | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Oxidative Stress and Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > NF-κB
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