DS-2969b

Overview

DS-2969b is an orally active GyrB inhibitor with antibacterial activity. DS-2969b is is active against Clostridium difficile infection (MIC 90 : 0.06 μg/mL), which is 2-, 16-, and 32-fold lower than those of Fidaxomicin ( HY-17580 ), Metronidazole ( HY-B0318 ), and Vancomycin ( HY-B0671 ), respectively. DS-2969b inhibits the supercoiling activity of C. difficile DNA gyrase. DS-2969b also exhibits activity against other Gram-positive anaerobes, including strict and facultative anaerobes. DS-2969b is safe and well tolerated in preclinical toxicology studies.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-116880
• CAS No.: 2092352-48-0
• Molecular Formula: C17H25ClN6O3S
• Molecular Weight: 428.94
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source