RO 5073012 is a selective, orally active and brain-penetrant TAAR1 agonist. RO 5073012 shows a K i of 6 nM for hTAAR1 and EC 50 values of 23 and 25 nM for mTAAR1 and rTAAR1. RO 5073012 can be used for the research of neurological disease , such as schizophrenia.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Schizophrenia | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Trace Amine-associated Receptor (TAAR)
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