L-735821

Overview

L-735821 is a Potassium channel blocker and an antagonist of I Ks . L-735821 inhibits the KCNQ1 channel activity with an EC 50 of 0.08 μM. L-735821 can increase I Ks and I Kr current-voltage relations in rabbit ventricular myocytes. L-735821 fully abolishes I Ks in isolated human ventricular myocytes at 100 nmol/L. L-735821 can easily enter single myocytes.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-117174
• CAS No.: 170228-29-2
• Molecular Formula: C25H19Cl2N3O2
• Molecular Weight: 464.34
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source