LP-403812 is a high affinity proline transporter ( PROT ) inhibitor that produces dose-dependent inhibition of hPROT ( IC 50 =0.11 μM; K i =0.12 μM) and also inhibits the activity of mouse brain synaptosomal mPROT with the same potency ( IC 50 =0.23 μM). LP-403812 can be used to study the function of PROT in the brain.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Amino acid Transporter
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