Homocarbonyltopsentin

Overview

Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2 -binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC 50 value of 16 μM.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Others | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-117389
• CAS No.: 172286-77-0
• Molecular Formula: C21H14N4O3
• Molecular Weight: 370.36
• Purity: 99.82%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (5.62 mM); Clear solution
• Availability: In-stock

Source

Original product source