JNJ-54175446

Overview

JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC 50 s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > P2X Receptor

Product Information

• Catalog No.: HY-117508
• CAS No.: 1627902-21-9
• Molecular Formula: C18H13ClF4N6O
• Molecular Weight: 440.78
• Purity: 98.84%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (4.72 mM); Clear solution
• Availability: In-stock

Source

Original product source