Alatrioprilat is an orally active inhibitor of angiotensin-converting enzyme ( ACE ) ( IC 50 =19.6 nM; K i =9.8 nM) and enkephailnase ( IC 50 =6.1 nM; K i =5.1 nM). Alatrioprilat plays a key role in the metabolism of hormonal peptides through the degradation of nitric oxide and atrial natriuretic factor (ANF). Alatrioprilat can be used in the study of cardiovascular diseases.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Neprilysin | Products > Signaling Pathways > Angiotensin-converting Enzyme (ACE)
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