Bisindolylmaleimide XI hydrochloride

Overview

Bisindolylmaleimide XI hydrochloride (Ro 32-0432) is a potent, selective and orally active PKC inhibitor with IC 50 s of 9 nM, 28 nM, 31 nM, 37 nM, and 108 nM for PKCα , PKCβI , PKCβII , PKCγ , and PKCε , respectively.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PKC

Product Information

• Catalog No.: HY-117610A
• CAS No.: 145333-02-4
• Molecular Formula: C28H29ClN4O2
• Molecular Weight: 489.01
• Purity: 98.91%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source