L-749329 ((Rac)-L-754142) is an ET A and ET B receptor antagonist, with K i s of 0.062 nM and 2.25 nM for ET A and ET B respectively. L-749329 inhibits ET-1-stimulated signaling.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Endothelin Receptor
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