(-)-BO 2367

Overview

(-)-BO 2367, an antimicrobial quinolone , is a strong mammalian and bacterial topoisomerase II inhibitor. (-)-BO 2367 shows IC 50 values with 3.8 μM, 0.5 μM, and 1 μM against the DNA relaxation activity of L1210 topoisomerase II and the supercoiling activities of Escherichia coli gyrase and Micrococcus luteus gyrase, respectively. (-)-BO 2367 is a potent antitumor agent.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-117657
• CAS No.: 145902-81-4
• Molecular Formula: C21H22ClF2N3O3
• Molecular Weight: 437.87
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source