Cabamiquine succinate

Overview

Cabamiquine (DDD107498) succinate is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite , with an EC 50 of 1 nM against P. falciparum 3D7. Cabamiquine succinate inhibits protein synthesis by targeting eEF2/CaMKIII , with an EC 50 of 2 nM for WT- Pf eEF2.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Parasitic Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Infection | Products > Signaling Pathways > Parasite | Products > Signaling Pathways > CaMK

Product Information

• Catalog No.: HY-117684A
• CAS No.: 2444781-71-7
• Molecular Formula: C31H37FN4O6
• Molecular Weight: 580.65
• Purity: 99.80%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.25 mg/mL (3.87 mM); Clear solution
• Availability: In-stock

Source

Original product source