Opelconazole

Overview

Opelconazole (PC945), a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus . Opelconazole is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B , with IC 50 s of 0.23 μM and 0.22 μM, respectively.

Application

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Product Information

• Catalog No.: HY-117766
• CAS No.: 1931946-73-4
• Molecular Formula: C38H37F3N6O3
• Molecular Weight: 682.73
• Purity: 98.41%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (3.66 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source