GSK2163632A is a selective G protein-coupled receptor kinase (GRK) inhibitor that can be used as a probe for studying heart failure and Parkinson's disease. GSK2163632A potently inhibits GRK1 and GRK5 , and also inhibits Rho-associated coiled-coil kinase ( ROCK ) and insulin-like growth factor receptor IGF-1R . GSK2163632A binds to GRK2 in a manner similar to Paroxetine ( HY-122272 ).
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > IGF-1R | Products > Signaling Pathways > ROCK | Products > Signaling Pathways > G Protein-coupled Receptor Kinase (GRK)
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