GNF-8625

Overview

GNF-8625 is a broad-spectrum TRK inhibitor that can combine with Thalidomide to form a PROTAC degrader. The IC50 of GNF-8625 for inhibiting TRKA , TRKB , and TRKC are 0.8 nM, 22 nM, and 5.4 nM, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Ligands for Target Protein for PROTAC | Products > Signaling Pathways > Trk Receptor

Product Information

• Catalog No.: HY-118271
• CAS No.: 1196546-33-4
• Molecular Formula: C31H30FN7O
• Molecular Weight: 535.61
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source