HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus ( HCV ) , that inhibits 1a and 1b HCV pseudoparticles with EC 50 of 0.134 and 0.027 μM. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV (HCVcc), with EC 50 of 0.024 and 0.012μM. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread.
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