SAS-0132

Overview

SAS-0132 is a selective Sigma 2 receptor ( Sig2R ) antagonist ( K i : 90 nM) that can cross the blood-brain barrier. SAS-0132 is capable of regulating intracellular Ca 2+ levels and modulating PGRMC1 -related pathways. SAS-0132 exhibits neuroprotective activity and can improve cognitive impairment in Alzheimer's disease mice. SAS-0132 can be used in the research of neurocognitive disorders such as Alzheimer's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sigma Receptor | Products > Signaling Pathways > Calcium Channel

Product Information

• Catalog No.: HY-119386
• CAS No.: 1644629-60-6
• Molecular Formula: C24H29N3O2
• Molecular Weight: 391.51
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source