Quininib is a cysteinyl leukotriene 1 and 2 receptor antagonist with IC 50 s of 1.2 and 52 μM for CysLT 1 R and CysLT 2 R , respectively. Quininib is a potent inhibitor of developmental angiogenesis in the zebrafish eye. Quininib can be used for the research of ocular neovascular pathologies and may complement current anti-VEGF biological agents.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Leukotriene Receptor
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