Medifoxamine

Overview

Medifoxamine is an orally active monoamine reuptake inhibitor and antidepressant. Medifoxamine preferentially inhibits presynaptic dopamine reuptake. Medifoxamine acts as an intraocular pressure-lowering agent to reduce intraocular pressure, and also functions as a miotic agent to decrease pupil diameter. Medifoxamine exhibits characteristic properties of antidepressant compounds, including preventing hypothermia induced by Reserpine ( HY-N0480 ) or Apomorphine ( HY-12723 ), potentiating the toxic effects of Yohimbine ( HY-N0127 ) in mice, and reducing immobility behavior in mice and rats in the "behavioral despair" model. Medifoxamine has no anticholinergic activity. Medifoxamine can be used in research related to depression.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Visual System Disease | Products > Disease Areas > Depression | Products > Disease Areas > Ocular Hypertension | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Transporter

Product Information

• Catalog No.: HY-119468
• CAS No.: 32359-34-5
• Molecular Formula: C16H19NO2
• Molecular Weight: 257.33
• Purity: 99.34%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (9.72 mM); Clear solution
• Availability: In-stock

Source

Original product source