(Rac)-Tavapadon

Overview

(Rac)-Tavapadon ((Rac)-PF-06649751) is a potent and selective noncatechol dopamine D1 receptor agonist. (Rac)-Tavapadon displays potent full agonism in the GS activation assay as well as partial agonism in the β-arrestin2 recruitment assay (GS-cAMP, EC 50 =0.8 nM; β-arrestin2, EC 50 =68 nM). (Rac)-Tavapadon has antiparkinsonian activity.

Application

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Product Information

• Catalog No.: HY-119486A
• CAS No.: 1643462-64-9
• Molecular Formula: C19H16F3N3O3
• Molecular Weight: 391.34
• Purity: 99.49%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 4.17 mg/mL (10.66 mM); Clear solution
• Availability: In-stock

Source

Original product source