Boscalid

Overview

Boscalid is a succinate dehydrogenase ( SDHI ) inhibitor with antifungal activity. Boscalid binds to the ubiquinone-binding site of fungal mitochondrial complex II, blocks ATP production and aerobic respiration, exhibits good control efficacy against a variety of plant fungal diseases including gray mold, sclerotinia rot and powdery mildew, and is widely used for disease control in agriculture. Boscalid induces apoptosis , altered lipid metabolism, mitochondrial dysfunction, respiratory impairment, oxidative stress, ROS accumulation and neurodevelopmental disorders in zebrafish. Boscalid reduces foraging ability, shortens median death time and causes chronic toxicity in exposed honeybees. Boscalid also possesses genotoxicity, cytotoxicity, elevated mitochondrial superoxide levels and early-stage apoptosis .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Fungal Infection | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Infection | Products > Signaling Pathways > Succinate Dehydrogenase | Products > Signaling Pathways > Environmental Pollutants | Products > Signaling Pathways > Mitochondrial Metabolism | Products > Signaling Pathways > Fungal | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-119976
• CAS No.: 188425-85-6
• Molecular Formula: C18H12Cl2N2O
• Molecular Weight: 343.21
• Purity: 99.80%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (7.28 mM); Clear solution
• Availability: In-stock

Source

Original product source