YM116

Overview

YM116 is an orally active and competitive CYP17A1 (17,20-lyase) inhibitor ( K i : 0.38 nM). YM116 reduces the synthesis of adrenal androgens by preferentially inhibiting C17-20 lyase activity. YM116 decreases the serum testosterone concentration, reduces dehydroepiandrosterone sulfate levels and decreases prostatic weights.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-120067
• CAS No.: 183012-13-7
• Molecular Formula: C16H13N3
• Molecular Weight: 247.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source