PF-06446846

Overview

PF-06446846 is an orally active proprotein convertase subtilisin/kexin type 9 ( PCSK9 ) inhibitor. PF-06446846 directly and selectively inhibits translation of PCSK9 by stalling the 80S ribosome in the proximity of codon region.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > PCSK9

Product Information

• Catalog No.: HY-120088
• CAS No.: 1632250-49-7
• Molecular Formula: C22H20ClN7O
• Molecular Weight: 433.89
• Purity: 98.35%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.76 mM); Clear solution
• Availability: In-stock

Source

Original product source