OAT-177

Overview

OAT-177 is a potent dual inhibitor targeting acidic mammalian chitinase ( AMCase ) and chitotriosidase ( CHIT1 ) with an IC 50 =14.2 nM for human AMCase and IC 50 =232 nM for human CHIT1. OAT-177 is promising for research of chronic inflammatory and fibrotic-related lung diseases such as asthma and idiopathic pulmonary fibrosis.

Application

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Product Information

• Catalog No.: HY-120107
• CAS No.: 1799548-33-6
• Molecular Formula: C19H29ClN6
• Molecular Weight: 376.93
• Purity: 99.90%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (6.63 mM); Clear solution
• Availability: In-stock

Source

Original product source