SM19712

Overview

SM19712 is an orally active, selective endothelin converting enzyme ( ECE ) inhibitor. SM19712 inhibits conversion of big ET-1 to ET-1 . SM19712 attenuates colonic angiogenesis, tissue injury, inflammation, without altering colon shortening or myeloperoxidase levels in mice. SM19712 can be used for the research of inflammatory bowel disease (colitis), ischemic acute renal failure, acute myocardial infarction, and myocardial ischemia/reperfusion injury.

Application

Products | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Oxidative Stress and Inflammation | Products > Disease Areas > Nervous System Injury | Products > Disease Areas > Heart Disease | Products > Disease Areas > Renal Disease | Products > Disease Areas > Inflammatory Bowel Disease | Products > Disease Areas > Ischemia-Reperfusion Injury | Products > Disease Areas > Myocardial Infarction | Products > Disease Areas > Renal Failure | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Urogenital Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Endothelin-Converting Enzyme (ECE) | Products > Signaling Pathways > Endothelin Receptor

Product Information

• Catalog No.: HY-120148A
• CAS No.: 194542-56-8
• Molecular Formula: C18H13ClN5NaO3S
• Molecular Weight: 437.84
• Purity: 99.0%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source