Elesclomol

Overview

Elesclomol (STA-4783) is a potent copper ionophore and promotes copper-dependent cell death ( cuproptosis ). Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand. Elesclomol inhibits FDX1-mediated Fe-S cluster biosynthesis. Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis . Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research.

Application

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Product Information

• Catalog No.: HY-12040
• CAS No.: 488832-69-5
• Molecular Formula: C19H20N4O2S2
• Molecular Weight: 400.52
• Purity: 99.19%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: ≥ 2.5 mg/mL (6.24 mM); Clear solution
• Availability: In-stock

Source

Original product source