BMS-193885

Overview

BMS-193885 is a selective neuropeptide Y1 receptor antagonist (K i =3.3 nM) that competitively blocks the receptor to inhibit NPY-mediated appetite regulation signaling pathways, reduce food intake and inhibit weight gain. BMS-193885 has good blood-brain barrier penetration and is mainly used in the study of obesity and related metabolic diseases.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Obesity | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Endocrinology | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Neuropeptide Y Receptor

Product Information

• Catalog No.: HY-120619
• CAS No.: 186185-03-5
• Molecular Formula: C33H42N4O6
• Molecular Weight: 590.71
• Purity: 99.91%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.23 mM); Clear solution
• Availability: In-stock

Source

Original product source