LY320954 is a selective 5-HT2A receptor antagonist, with a K i of 96 nM. LY320954 potently inhibits Ca 2+ influx in the functional assay (EC 50 of 35.5 nM). LY320954 inhibits 5-HT-induced paw swelling in rats, with ED 50 of 4.8 mg/kg.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor
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