Adatanserin (WY-50324) is a high affinity, selective and partial agonist for the 5-HT 1A receptor with a K i of 1 nM. Adatanserin is a moderate affinity 5-HT 2 receptor antagonist with a K i of 73 nM. Adatanserin shows significant anxiolytic and antidepressant activity in an animal conflict model.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor
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