S 1360

Overview

S 1360 is a potent and selective inhibitor of HIV-1 integrase . S 1360 inhibits the catalytic activity of purified integrase ( IC 50 : 20 nM). The EC 50 , and CC 50 of S 1360 in MTT assay (MT-4 cells infected with HIV-1 IIIB) are 200 nM and 12 μM, respectively. S 1360 has antiviral activity against both X4 tropic and R5 tropic strains, as well as NRTI, NNRTI and PI drug-resistant variants.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > HIV Integrase | Products > Signaling Pathways > HIV

Product Information

• Catalog No.: HY-12108
• CAS No.: 280571-30-4
• Molecular Formula: C16H12FN3O3
• Molecular Weight: 313.28
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source