Bactobolin hydrochloride (Compound 1) is an antibiotic , which inhibits Escherichia coli , Salmonella , Shigella , Staphylococcus and Bacillus subtilis , with MIC s of 0.3-6.25 μg/mL. Bactobolin hydrochloride exhibits antitumor efficacy against leukemia, with a LD 50 value of 6.25-12.5 mg/kg.
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