AZ1729

AZ1729
  • CAS No.:2016864-46-1
  • Grade:99.98%
  • Formula:C18H16FN5OS
  • M.W.:369.42

Overview

AZ1729 is a potent free fatty acid 2 receptor (FFA2) activator, acting as a direct allosteric agonist and as a positive allosteric modulator. AZ1729 increases the activity of the endogenously produced short chain fatty acid propionate in G i -mediated pathways, but not at those transduced by G q /G 11 . AZ1729 induces inhibition of isoproterenol-induced lipolysis in mouse adipocytes. AZ1729 also can Induce migration of human neutrophils. AZ1729 can be used for researching the signaling pathways of the physiological roles of FFA2.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Free Fatty Acid Receptor

Product Information

  • Catalog No.: HY-121140
  • CAS No.: 2016864-46-1
  • Molecular Formula: C18H16FN5OS
  • Molecular Weight: 369.42
  • Purity: 99.98%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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