Chlorasquin

Overview

Chlorasquin inhibits thymidylate synthetase with an approximate K i value of 4.9 μM. Chlorasquin is also a folate antagonist, testing the Methotrexate ( HY-14519 ) effect. Chlorasquin binds tighter to dihydrofolate reductase at alkaline pH than does Methotrexate , which is promising for research of antipsoriatic agents.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Thymidylate Synthase | Products > Signaling Pathways > Antifolate | Products > Signaling Pathways > Dihydrofolate reductase (DHFR)

Product Information

• Catalog No.: HY-121256
• CAS No.: 18921-73-8
• Molecular Formula: C20H19ClN6O5
• Molecular Weight: 458.86
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source