α-Thujone

α-Thujone
  • CAS No.:546-80-5
  • Grade:98.07%
  • Formula:C10H16O
  • M.W.:152.24
  • Solvent:≥ 2.5 mg/mL (16.42 mM); Clear solution

Overview

α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC 50 for α-Thujone is 21 μM in suppressing the GABA -induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy . α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and can cross the blood-brain barrier.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Others | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > Environmental Pollutants | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Parasite | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > GABA Receptor | Products > Signaling Pathways > Apoptosis

Product Information

  • Catalog No.: HY-121618
  • CAS No.: 546-80-5
  • Molecular Formula: C10H16O
  • Molecular Weight: 152.24
  • Purity: 98.07%
  • Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 2.5 mg/mL (16.42 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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