2-Bromo-LSD D-Tartrate

Overview

2-Bromo-LSD D-Tartrate (BOL-148 D-Tartrate) is a blood-brain barrier-permeable 5-HT 2A partial agonist and competitive partial antagonist. 2-Bromo-LSD D-Tartrate acts as both a potent partial agonist (with an EC 50 of 0.81 nM for Gq dissociation) and a potent partial antagonist (with a K B of 0.18 nM for Gq dissociation) at the 5-HT 2A receptor. 2-Bromo-LSD D-Tartrate exhibits partial agonist activity at multiple aminergic GPCR s, including 5-HT 2A . 2-Bromo-LSD D-Tartrate lacks 5-HT 2B agonist activity. 2-Bromo-LSD D-Tartrate induces dendritogenesis and spinogenesis. 2-Bromo-LSD D-Tartrate reverses the behavioral effects of chronic stress and increases active coping behaviors in mice.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > G protein-coupled Bile Acid Receptor 1

Product Information

• Catalog No.: HY-121675A
• CAS No.: 2855123-30-5
• Molecular Formula: C20H24BrN3O·1/2C4H6O6
• Molecular Weight: 477.39
• Purity: 99.91%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (5.24 mM); Clear solution
• Availability: In-stock

Source

Original product source