FR 78844 is an orally active bone resorption inhibitor. FR 78844 attenuates metaphyseal bone mineral density decreases in Streptozotocin ( HY-13753 )-induced diabetic rats, and Heparin ( HY-17567A )-induced osteopenia, but does not affect vitamin D-deficient rat bone loss. FR 78844 can be used for the research of osteopenia.
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