ACG548B (compound 24) is a potent inhibitor of acetyl- and butyrylcholinesterase ( AChE and BChE ) with IC 50 s of 1.78 and 0.496 μM, respectively. ACG548B has higher AChE affinity and selectivity over BChE and ChoK ( choline kinase ). ACG548B can be uesd for the study of myasthenia gravis and neuromuscular blockade.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE)
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