GBR 12935 dihydrochloride

Overview

GBR 12935 dihydrochloride is a potent, and selective dopamine reuptake inhibitor, with the binding constant (K d ) of 1.08 nM in COS-7 cells. GBR 12935 dihydrochloride stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 dihydrochloride also prevents the d-Fenfluramine-induced head-twitch response in mice.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Transporter

Product Information

• Catalog No.: HY-12242
• CAS No.: 67469-81-2
• Molecular Formula: C28H36Cl2N2O
• Molecular Weight: 487.50
• Purity: 99.80%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (5.13 mM); Clear solution
• Availability: In-stock

Source

Original product source