Lovastatin acid (Mevinolinic acid; MSD803), an active metabolite of Lovastatin ( HY-N0504 ), is a potent competitive HMG-CoA reductase inhibitor with a K i of 0.6 nM. Lovastatin acid acts as a competitive inhibitor with respect to substrate HMG-CoA, interfering cholesterol synthesis. Lovastatin acid can be used for the research of hypercholesterolemia.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Hypercholesterolemia | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > HMG-CoA Reductase (HMGCR) | Products > Signaling Pathways > Drug Metabolite
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