VHL Ligand 38

Overview

VHL Ligand 38 (Compound 1) is a competitive E3 ubiquitin-protein ligase VHL inhibitor with IC 50 s of 4.1 and 7.0 μM in 1% and 10% DMSO, respectively. VHL Ligand 38 contains a hydroxyproline residue and an isoxazolylacetamide fragment. VHL Ligand 38 significantly inhibits the binding of a fluorescent peptide derived from HIF1α (FAM-DEALA-Hyp-YIPD) ( HY-P5908F ) to VHL.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > E1/E2/E3 Enzyme

Product Information

• Catalog No.: HY-122570
• CAS No.: 1360616-29-0
• Molecular Formula: C21H22N4O5
• Molecular Weight: 410.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source