S29434

Overview

S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2) , with IC 50 s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 induces autophagy and inhibits QR2-mediated ROS production.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-122614
• CAS No.: 874484-20-5
• Molecular Formula: C21H18N4O3
• Molecular Weight: 374.39
• Purity: 99.29%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2 mg/mL (5.34 mM); Clear solution
• Availability: In-stock

Source

Original product source