Umbralisib

Overview

Umbralisib (TGR-1202) is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε ( CK1ε ) inhibitor, with EC 50 of 22.2 nM and 6.0 μM, respectively. Umbralisib exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib can be used for haematological malignancies reseach.

Application

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Product Information

• Catalog No.: HY-12279
• CAS No.: 1532533-67-7
• Molecular Formula: C31H24F3N5O3
• Molecular Weight: 571.55
• Purity: 98.94%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2 mg/mL (3.50 mM); Clear solution
• Availability: In-stock

Source

Original product source