(Rac)-Z-FA-FMK

Overview

(Rac)-Z-FA-FMK is the racemate of Z-FA-FMK. (Rac)-Z-FA-FMK is an inhibitor of cathepsin B with a K i of 1.5 μM. (Rac)-Z-FA-FMK inhibits caspase-2, -3, -6, -7, and -9 with IC 50 s of 6.147, 15.41, 32.45, 9.077, and 110.7 μM. (Rac)-Z-FA-FMK inhibits the main protease of SARS-CoV-2 replication with an IC 50 of 11.39 μM. (Rac)-Z-FA-FMK inhibits the increased IL-1β level induced by LPS and NF-κB transactivation in macrophages.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Infection | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Cathepsin | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > SARS-CoV

Product Information

• Catalog No.: HY-123185
• CAS No.: 96922-64-4
• Molecular Formula: C21H23FN2O4
• Molecular Weight: 386.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source