RL648_81

Overview

RL648_81 is a specific KQT-like subfamily 2/3 (KCNQ2/3) activator with an EC 50 of 190 nM. RL648_81 robustly shifts the V1/2 of KCNQ2/3 channels towards hyperpolarized potentials.RL648_81 does not shift the V1/2 of either KCNQ4 or KCNQ5.RL648_81 has?the?potential?for?neurologic disorders associated with neuronal hyperexcitability research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-123264
• CAS No.: 1919050-87-5
• Molecular Formula: C17H17F4N3O2
• Molecular Weight: 371.33
• Purity: 99.49%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.73 mM); Clear solution
• Availability: In-stock

Source

Original product source