c-di-AMP disodium

Overview

c-di-AMP (Cyclic diadenylate) sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP sodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > STING | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-12326A
• CAS No.: 2734909-87-4
• Molecular Formula: C20H22N10Na2O12P2
• Molecular Weight: 702.38
• Purity: 99.14%
• Storage: -80°C, protect from light, stored under nitrogen
• Solubility: ≥ 6.75 mg/mL (9.61 mM); Clear solution
• Availability: In-stock

Source

Original product source