Ro 61-8048

Overview

Ro 61-8048 is an orally active and selective inhibitor of kynurenine 3-hydroxylase , with an IC 50 of 37 nM. Ro 61-8048 provokes a significant increase of extracellular kynurenic acid concentrations.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > KMO

Product Information

• Catalog No.: HY-12347
• CAS No.: 199666-03-0
• Molecular Formula: C17H15N3O6S2
• Molecular Weight: 421.45
• Purity: 99.93%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.93 mM); Clear solution
• Availability: In-stock

Source

Original product source