JNJ 10329670 is a potent and selective noncovalent cathepsin S inhibitor with a K i value of 34 nM for human cathepsin S . JNJ 10329670 blocks invariant chain proteolysis in B cells and dendritic cells, as well as antigen-induced T cell proliferation.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Cathepsin
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