GGTI-2133 TFA

Overview

GGTI-2133 TFA, a peptidomimetic, is a selective geranylgeranyltransferase I (GGTase-I) inhibitor with an IC 50 of 38 nM. GGTI-2133 TFA shows 140-fold selectivity over farnesyltransferase (FTase) ( IC 50 of 5.4 μM). GGTI-2133 TFA inhibits the geranylation of Rap-1A with an IC 50 of 10 μM. GGTI-2133 TFA can be used for the study of eosinophilic airway inflammation such as asthma.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > GGTase

Product Information

• Catalog No.: HY-12369A
• CAS No.: 1217480-14-2
• Molecular Formula: C29H29F3N4O5
• Molecular Weight: 570.56
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source