PF-03654764 is an orally active, selective histamine H 3 receptor antagonist with K i values of 1.2 nM and 7.9 nM for human H 3 and rat H 3 in whole cell assay, respectively. The combination of PF-03654764 and Fexofenadine ( HY-B0801A ) has the potential for allergic rhinitis research.
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