LY3020371 hydrochloride

Overview

LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor ( mGlu2/3 ) antagonist with K i of 5.3 and 2.5 nM, potently blocks cAMP formation with IC 50 of 16.2 nM. LY3020371 hydrochloride exerts an antidepressant-like signature in vivo.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Depression | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mGluR

Product Information

• Catalog No.: HY-123820
• CAS No.: 1377615-44-5
• Molecular Formula: C15H16ClF2NO5S
• Molecular Weight: 395.81
• Purity: 99.18%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (5.26 mM); Clear solution
• Availability: In-stock

Source

Original product source